On His Debut Album,
For You,
Prince played 27 instruments

Besides using his voice, which in itself is an instrument, Prince listed the following instruments used on this and most certainly subsequent albums: guitars, orr bass, Poly Moog, Syndrums, Arp Pro Soloist, Arp String Ensemble, synthesizer bass, drums, clavinet, Oberheim 4 voice, slapsticks, finger cymbals, wind chimes, congas, electric guitars, water drums, bongos, Fender Rhodes piano, mini Moog, fuzz bazz, acoustic piano, orchestra bells, wood blocks, brush trap, tree bell, acoustic guitar
Check out this article for more details on this phenomenal musician.